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Due to the use of lidocaine hydrochloride diluent, this product is contraindicated in patients with a known hypersensitivity to local anesthetics of the amide type and in patients with severe shock or heart block. These data are similar to those described after shorter periods of administration of lidocaine during labor. Local side effects reported with the use of lidocaine topical patch were generally experienced during or immediately following treatment. Nervous system side effects associated with lidocaine topical patch have included paresthesia, hyperesthesia, hypoesthesia, headache, dizziness, lightheadedness, nervousness, somnolence, disorientation, and confusion. The free fraction of lidocaine in neonates may be higher than in the mother due to decreased plasma protein binding. in lidocaine HCl should be used within one hour after preparation. GastrointestinalGastrointestinal side effects associated with lidocaine topical patch have included metallic taste, taste alteration, nausea, and vomiting. You will need to discuss the benefits and risks of using Lidocaine/Hydrocortisone Cream while you are pregnant. Drowsiness may be an early clinical symptom of high lidocaine serum levels. In another case, lidocaine and its metabolite, MEGX, were found in breast milk after injection of lidocaine 20 mg for a dental procedure. OtherOther side effects associated with lidocaine topical patch have included asthenia, tinnitus, tremor, and flushing. OcularOcular side effects associated with lidocaine topical patch have included visual disturbances and blurred vision. ) For additional precautions, refer to the package circular for lidocaine HCl. 1 g of lidocaine (50 mg/hr for 282 hours), the umbilical vein/maternal vein lidocaine concentration ratio averaged 0. If you are or will be breast-feeding while you use Lidocaine Solution, check with your doctor. If you are or will be breast-feeding while you use Lidocaine/Hydrocortisone Cream, check with your doctor. You will need to discuss the benefits and risks of using Lidocaine Solution while you are pregnant. These data do not support an association between lidocaine and birth defects. Lidocaine should only be given during pregnancy and in labor and delivery when need has been clearly established. Nervous system side effects associated with systemic lidocaine have included lightheadedness, nervousness, apprehension, euphoria, confusion, dizziness, drowsiness, tinnitus, blurred or double vision, vomiting, sensations of heat, cold, or numbness, twitching, tremors, convulsions, unconsciousness, respiratory depression, and respiratory arrest. HypersensitivityHypersensitivity reactions associated with systemic lidocaine have rarely included urticaria, angioedema, bronchospasm, laryngospasm, dermatitis, pruritus, dyspnea, and shock. This effect is typically the result of the presence of dried lidocaine topical jelly residue in the inner lumen of the tube. CardiovascularCardiovascular side effects associated with systemic lidocaine have included bradycardia, hypotension, and cardiovascular collapse leading to possible cardiac arrest.

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